A discovery promises to improve care for patients with endometrial cancer, the most common gynecologic malignancy. Using artificial intelligence (AI) to spot patterns across thousands of cancer cell images, the researchers have pinpointed a distinct subset of endometrial cancer that puts patients at much greater risk of recurrence and death, but would otherwise go unrecognized by traditional pathology and molecular diagnostics. The findings will help doctors identify patients with high-risk disease who could benefit from more comprehensive treatment.